ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden.The globally dominant sequence type 239 (ST239) HA-MRSA clone has persisted in the health care setting for decades, but the basis of its success has not been identified.Taking a collect
Dictyostelium centrosomes consist of a nucleus-associated cylindrical, three-layered core structure surrounded by a corona consisting of microtubule-nucleation complexes embedded in a scaffold of large coiled-coil proteins.One of them is the conserved CDK5RAP2 protein.Here we focus on the role of Dictyostelium CDK5RAP2 for maintenance of centrosome
The involvement of the phytohormone ethylene as the main trigger of climacteric fruit ripening is well documented.However, our knowledge regarding the role of ethylene response factor (ERF) transcription Liquid Soap factor in the transcriptional regulation of ethylene biosynthesis during fruit ripening remains limited.Here, comprehensive transcript
Abstract Background Although low-grade serous Alternator Controller ovarian cancer (LGSC) is rare, case-fatality rates are high as most patients present with advanced disease and current cytotoxic therapies are not overly effective.Recognizing that these cancers may be driven by MAPK pathway activation, MEK inhibitors (MEKi) are being tested in cli
Natural stone has been used since the dawn of civilization as a construction material for buildings that are historical and cultural buildings and monuments.The Zagreb Cathedral is an example of such a historical and cultural building and data regarding the extraction of stone for its construction and reconstruction is scientifically underestimated